Recurrence of adrenal aldosterone-producing adenoma

Factors Determining Outcomes in Aldosterone-Producing Adrenal Adenoma

Division of Nephrology, Department of Internal Medicine, Chang Gung Memorial Hospital-Kaohsiung Medical Center, Chang Gung University College of Medicine, Kaohsiung, Taiwan Department of Urology, Chang Gung Memorial Hospital-Kaohsiung Medical Center, Chang Gung University College of Medicine, Kaohsiung, Taiwan Division of Cardiology, Department of Internal Medicine, Chang Gung Memorial Hospital...

Hypomethylation of CYP11B2 in Aldosterone-Producing Adenoma.

The purpose of this study was to evaluate the DNA methylation levels of steroidogenic enzyme genes in aldosterone-producing adenoma (APA) and the effects of gene mutations in APA on the DNA methylation levels. DNA methylation array analysis was conducted using nonfunctioning adrenocortical adenoma (n=12) and APA (n=35) samples, including some with a KCNJ5 mutation (n=21), an ATP1A1 mutation (n=...

CTNNB1 Mutation in Aldosterone Producing Adenoma

Discoveries of somatic mutations permit the recognition of subtypes of aldosterone-producing adenomas (APAs) with distinct clinical presentations and pathological features. Catenin β1 (CTNNB1) mutation in APAs has been recently described and discussed in the literature. However, significant knowledge gaps still remain regarding the prevalence, clinical characteristics, pathophysiology, and outc...

[Laparoscopic partial adrenalectomy for aldosterone-producing adenoma].

AB203. The mutational landscapes of adrenal cortex aldosterone-producing adenoma (APA) diversified between different populations

© Translational Andrology and Urology. All rights reserved. Transl Androl Urol, 2015;4(S1) www.amepc.org/tau explored. Small-interfering RNA (siRNA) was used to suppress CENPH expression in RCC cell lines. In vitro assays were performed to further explore its role in tumor progression. Results: The expression level of CENPH was higher in ccRCC tissues and cell lines than in corresponding adjace...